In the second case, the abscess was proven to have no communication with the anastomosis, as evidenced by lack of contrast extravasation on imaging and a lack of air within the abscess cavity. Therefore, this abscess was deemed not related to an anastomotic leak. These 2 patients with abscesses were treated with only antibiotics and had complete resolution, with no other intervention. There were 2 patients who received postoperative antibiotics beyond the 24-hour postoperative period; both patients were treated for abscess or

phlegmon found during the index operation for diverticular disease, and antibiotics were discontinued by postoperative day 4. All recorded fevers had an attributable source as listed in Table 4, including urinary tract infection, wound infection, and/or Clostridium difficile infection. Two (1.4%) Lenvatinib anastomotic leaks were clinically suspected and radiologically confirmed (Table 5). Both patients had undergone low ligation of the IMA with an end-to-end anastomosis without diversion. One patient had rectal cancer with no history

of preoperative chemotherapy or radiation and underwent a 6-hour laparoscopic see more anterior resection with splenic flexure mobilization with anastomosis at 6 cm. A defect of the anastomosis was demonstrated on CT scan, which was obtained due to clinical suspicion on postoperative day 12. The patient was treated with a readmission, antibiotics, and transgluteal percutaneous drainage without diversion. The second patient had a diagnosis of diverticulitis and underwent

a 3-hour laparoscopic anterior resection with anastomosis at 11 cm. A CT scan performed on postoperative day 12 due to clinical suspicion of a leak showed a small abscess containing air adjacent to the anastomosis. The patient was treated with readmission and antibiotics. Both patients had complete resolution of symptoms without any further treatment. Table 6 lists outcomes with regard to high-risk (anastomosis < 10 cm and/or pelvic radiation) vs low-risk (≥10 cm and no radiation) patient Fenbendazole populations. Anastomotic leak is a significant complication of colorectal resection and leads to increased length of stay, cost, local recurrence, and mortality rates.4 and 5 Factors leading to anastomotic leak include patient characteristics, anastomotic integrity, and viability. Perfusion and tissue viability remain an area in which improvement may be achieved with the introduction of new technology. The ability to assess intraoperative perfusion accurately via easy to use and accessible methods is, therefore, of potential importance. This clinical trial demonstrated that PINPOINT is feasible and safe with no reported adverse events. Successful imaging was obtained in 98.6% of cases. Perfusion imaging led to a change in surgical plan in 7.9% of patients; all of these patients were discharged without any reported severe complications.