Findings were negative from blood and urine cultures, serological tests for the HIV and brucellosis, and sputum tests for Mycobacterium tuberculosis. A percutaneous biopsy of the L3-L4 disc was performed but the bacteriological studies recovered no organisms. A second needle biopsy was performed for broad-range 16S rDNA PCR testing, which identified C. canimorsus.
Conclusion. Broad-range PCR provided the microbiological diagnosis of culture-negative discitis in our patient. Broad-range
PCR should be Crenigacestat inhibitor considered in patients with culture-negative osteoarticular infections.”
“Little data are available on the outcome of tension-free obturator tape (TVT-O) procedures in obese and overweight women. We hypothesized that the subjective and objective outcomes of TVT-O in women with a higher body mass index (BMI) would differ from those with a lower BMI.
We retrospectively reviewed the records of 129 patients who had undergone TVT-O, stratifying by BMI into normal weight (n = 39), overweight (n = 58), and obese (n = 32) groups. We compared pre- and postoperative evaluations, including subjective and objective outcome of TVT-O, complications, and quality of life assessed by validated questionnaires.
The median follow-up was 24 months. There were no significant differences between
groups in terms of objective cure rate and subjective success, quality of life scores, or postoperative complications.
BMI did not influence the outcome of TVT-O procedures at a median of 24 months after surgery.”
“To investigate the efficacy of wide local excision as a surgical treatment for early-stage vulvar melanomas.
Wide CAL101 local excision with or without lymph node dissection was performed in three patients with stage I vulvar melanoma (American Joint Committee on Cancer classification, 1992).
All three patients were successfully treated by wide local excision. There was no evidence of recurrence at long-term follow-up in any of the patients.
Wide local excision with adequate tumor-free margins should be considered the treatment of choice for early-stage LY3039478 vulvar melanomas.”
“Study Design. Case report.
Objective. We present a case of myositis
ossificans (MO) of the upper cervical spine in a young child. The literature is reviewed with the classification, etiology, and treatment of MO discussed.
Summary of Background Data. Calcification of joint capsule, muscle, cartilage, and ligaments is a well-known phenomenon and is known as myositis ossificans. It is very rarely seen in the head and neck, with no reports of MO of the soft tissues surrounding the first 2 cervical vertebrae.
Methods. An 8-year-old boy presented with severe neck pain after a fall. He had had a similar neck injury 4 years before, but made a full recovery. Radiographs showed a large ossified lesion between the posterior elements of C1 and C2. After further imaging, a diagnosis of MO was made.