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“Figure options Download full-size image Download high-quality image (377 K) Download as PowerPoint slideIt is with great sorrow that I inform the Scientific Community of Cardiovascular Pathologists that Marcos A. Rossi, Professor of Pathology in Ribeirao Preto, Brazil, passed away prematurely due to acute myocardial infarction on May 9, 2013. He graduated at the Faculty of Medicine in Ribeirao Preto, which is under the rule of the University of Sao Paulo and where he did all his career: PhD in 1970,

Lecturer in 1977, Associate Professor in 1981, Full Professor (“Professor Titular”) in 1986 at the early age of 42. In 1971–72 he spent a Post-Doc period in the Department of Pathology at the Mount Sinai School of Medicine in New York, led by Prof. Hans Popper, the discoverer of liver architecture, where he learnt the technique of electron microscopy. Enzalutamide order Back in Ribeirao, he set up a laboratory

of ultrastructure, then became an outstanding electron mycroscopist under the mentorship of Professor Fritz Koberle, an Austrian pathologist, colleague of Prof. Popper in Wien, who advanced the neurogenic theory of Chagas disease accounting for megaesophagus, megacolon and dilated cardiomyopathy. By the way this was the topic of Marcos Rossi’s Ph.D. thesis. AT13387 in vivo The experience at the Mount Sinai in New York was a breakthrough for his career as experimental cardiovascular scientist in a developing country. Marcos Rossi was very productive

and wrote 261 full papers (and others in press) and 23 book chapters. His research has been consistently supported from Brazilian Agencies by nearly 60 grants. Worth to be mentioned are his contributions on Chagas cardiomyopathy, with special references on coronary microvasculopathy and Megestrol Acetate progression of Chagas myocarditis towards chronic dilated cardiomyopathy, on myocardial damage and subcellular events occurring during sepsis (a phenomenon which he called “septic cardiomyopathy”) and, more recently, on molecular mechanisms of cardiotoxicity by anthracycline. At the first International Symposium on Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia (ARVC/D) in 1996, held in Paris, his group presented the pathology of Chagas cardiomyopathy, which may affect the right ventricle with aneurysms, thus mimicking ARVC/D. Later on, in 1997, I met him for the first time when he came to my Institute as Visiting Professor (March 24, 1997) and delivered a lecture on Chagas disease. He had the opportunity to see the famous Anatomical Theatre of Fabrici ab Acquapendente, built in 1594, an experience which fascinated him. On October 2010, he invited me to Sao Paulo at the Biennial Meeting of the International Academy of Pathology, where he was committed to organize a Symposium on Advances on Cardiovascular Pathology and gave me the task to cover the topic of Molecular Pathology of Sudden Cardiac Death.