67, p < 0.01) and EXIT (F = 8.77, p < 0.03) scores. An interaction between APOE epsilon 4 carrier status and treatment (p = 0.05) was observed for both outcome measures.\n\nConclusion: In this open-label trial, among APOE epsilon 4 non-carriers, we observed stabilization of cognition and improvement in executive function among treated individuals compared with non-treated individuals. Among APOE epsilon 4 carriers, cognitive stabilization was evident for treated individuals whereas
a cognitive decline was observed in non-treated individuals. These findings provide additional evidence for potential therapeutic efficacy of nilvadipine in treating AD and warrant further investigation. Copyright (C) 2011 John Wiley & Sons, Ltd.”
“Overview: Leptospirosis is a bacterial HKI-272 research buy disease affecting a variety of domestic and wild animals as well as humans worldwide. Leptospirosis has find more been reported in over 150 mammalian species. It is considered an emerging infectious disease in humans and in dogs. Subclinically infected wild and domestic animals serve as reservoir hosts and are a potential source of infection for incidental hosts and humans.\n\nInfection: Reports of leptospirosis in cats are rare, but the importance of cats shedding Leptospira species and serving as a source of infection has recently gained attention. Leptospira species antibodies are commonly present
in the feline population, and Leptospira species shedding of cats with outdoor exposure has been demonstrated.
Cats mostly become infected through transmission from hunting rodents.\n\nSignificance: The role of healthy carrier cats as a source of contamination, as well as the role of leptospires as a pathogen in cats, are likely underestimated.”
“The assessment of spinal flexibility is essential for the planning of adolescent idiopathic scoliosis (AIS) surgery. Various radiographic methods have been used but none of them has shown any superiority. The new low-dose stereography system EOS (EOS imaging, Paris, France) VX-689 mouse captures whole body images in a single scan without vertical distortion. EOS is now used in routine clinical use for AIS follow-up. The aim of this study was to prospectively evaluate the feasibility and the reproducibility of a new suspension test during the EOS imaging for the assessment of spinal flexibility in AIS. Fifty AIS patients scheduled for surgery were prospectively included. For each patient, a standard EOS radiograph was obtained, then a suspension test in the EOS and a classic traction test on the cotrel frame were performed. The examinations were compared in terms of radiation exposure, tolerance, mean traction force, and Cobb angle reduction for each curve. Axial and sagittal reductions during suspension were analyzed on three-dimensional EOS reconstructions.