9; 75th:1.6; 95th:5.5; IQR:0.71), respectively. DAPT chemical structure The serum lactate levels of patients poisoned by FGAEs were significantly higher (p < 0.001). There was no significant difference among the patient groups poisoned by FGAEs and SGAEs in terms of age, GCS score, and the length of hospitalization (p= 0.459, p= 0.055, and p= 0.774, respectively) (Table 6). We assessed the cases poisoned by carbamazepine, the most frequent cause of intoxication in our study, in terms of association between the serum carbamazepine

level and the age, the GCS score and also between the serum lactate level and the systolic blood pressure on admission to emergency medicine. We divided the carbamazepine poisoning patients into 3 groups according to serum carbamazepine levels as follows:

Under 15 mg/L (Group 1, n = 12), between 15-30 mg/L (Group 2, n = 13), and over 30 mg/L (Group 3, n = 13). We observed that in the group with high levels of carbamazepine levels, GCS score was significantly lower, and the serum lactate level was significantly higher (p = 0.004 and p < 0.001). When the cause of these differences was evaluated, we found a statistically significant difference between Group 3 and Group 1 in terms of GCS score (p= 0.001). There was also a significant difference between Group 1 and Group 3, as well as, between Group 2 and Group 3 in terms of the serum lactate level (p < 0.001 and p < 0.001, respectively). There was no difference in terms of age and systolic blood pressure between the groups (p= 0.142 and p = 0.081) (Table 7). Likewise, selleck chemical there was a significant positive correlation between the serum carbamazepine level and the serum lactate level, and a significant negative correlation between the serum carbamapezine level and

GCS score (kk = 0.602, p < 0.001; and kk= -0.568, p < 0.001, respectively) (Table 9). We assessed the cases poisoned by VPA, the second most frequent cause of intoxication in our series, in terms of the association between serum VPA level and age, the GCS score, and also between the serum lactate level and the systolic blood pressure at the time of presentation. We Janus kinase (JAK) divided the VPA poisoning patients into 3 groups according to serum VPA levels as follows: Under 100 mg/L (Group 1, n = 7), between 100-125 mg/L (Group 2, n = 10), and over 125 mg/L (Group 3, n = 9). There was no significant difference between the serum VPA level and GCS score, nor between the serum VPA level and the serum lactate level and the systolic blood pressure (p = 0.470, p = 0.897, p = 0.088, respectively) (Table 8). Likewise, there was no significant correlation between the serum VPA level and the serum lactate level, nor between the serum VPA level and the GCS score, the systolic blood pressure, and age (kk = 0.132, p = 0.520; kk = -0.185, p = 0.130, kk = -0.286, p = 0.156, kk= 0.171, p = 0.404, respectively) (Table 9) However, there was a significant positive correlation between the serum VPA level and the serum ammonia level (kk = 0.742, p < 0.001).