Community-based health check-up information was collected in the Health Management Center of the First People’s Hospital of Shunde. The centres provided data for participants selleck compound who enrolled in their health check-up programmes conducted between January 2011 and December 2013. Participants
aged ≥35 years with complete data for the following characteristics were included in this study: age, sex, smoking/drinking habits, history of chronic diseases and treatment, family history of hypertension, height, weight, BP, fasting plasma glucose (FPG), total cholesterol (TC), triglycerides (TG), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), serum creatinine (Scr), blood urea nitrogen and serum uric acid (UA). BP measurement Although our data were based on retrospective analysis of community-based health check-up information, the protocol of BP measurement in our Health Management Center is carried out consistently since the foundation of the department. Participants were asked to avoid caffeinated beverages, smoking and exercise for at least 30 min,
and BP measurements were taken after the participants were allowed to rest quietly for at least 5 min. Three BP measurements (2 min between each) were obtained for each individual by trained nurses, who were part of the Health Management Center, with a mercury sphygmomanometer. The first and fifth Korotkoff sounds were recorded as SBP and DBP, respectively. During the measurements, the participants were seated with the arm supported at the level of the heart. The mean of three BP measurements was calculated and recorded. Definition of correlative risk factors The correlative risk factors estimated in our study included the following: (1) BP classification was based on the recommendations from the JNC 7.1 Optimal BP was defined as SBP <120 mm Hg and DBP <80 mm Hg. Hypertension was defined as SBP ≥140 mm Hg and/or DBP ≥90 mm Hg, or previously diagnosed as hypertension Carfilzomib and currently undergoing antihypertensive
treatment. Prehypertension was defined if individuals were not undergoing antihypertensive treatment and had an SBP of 120–139 mm Hg and/or DBP of 80–89 mm Hg. Prehypertension was further divided into low-range (SBP 120–129 and/or DBP 80–84 mm Hg) and high-range (SBP 130–139 mm Hg and/or DBP 85–89 mm Hg) subgroups. (2) Impaired glucose regulation was diagnosed based on FPG according to the American Diabetes Association criteria,10 including diabetes mellitus (DM; FPG ≥7.0 mmol/L) and impaired fasting glucose (IFG, FPG 5.6–6.9 mmol/L). Dyslipidaemia was defined as with a history of receiving antidyslipidaemia agents or TC ≥5.18 mmol/L, LDL-C ≥3.37 mmol/L, HDL-C <1.04 mmol/L and/or TG ≥1.