MDA level was significantly elevated in MSG (high dose) treated group as compared with normal control group, followed by significant increase in both MSG (medium and low dose treated groups) with respect to normal control group. Meanwhile, groups treated with MSG (high dose) co-administered with either vit E (High or low dose) afforded significant increase in MDA level when compared with normal

control group, while elicited significant decrease when compared with MSG treated groups either (high, med or low doses. The MSG (high dose) ZVADFMK plus Se either at high or low dose afforded significant decrease in MDA level as compared with MSG-treated groups in three doses and these were the best ameliorative results that succeeded in decreasing MDA levels after treatment of rats with MSG co-administered with Se. On the other hand, the Se-treated groups either in high or low dose elicited non-significant increase in MDA levels as compared to control group. Meanwhile, vit E (high dose) elicited a significant decrease in MDA level as compared to normal control group, while vit E (high dose) elicited non-significant changes in MDA level as compared to control group (Table 1). Table 1 revealed that the administration of MSG in three doses (high, med and low dose) to rats induced highly significant

decrease in CAT activities as compared to control group. Meanwhile rats treated with either vi E (in low or high dose) and/or Se (in either low or high dose) exhibited non-significant changes in CAT activity when compared with control group. On the other hand, MSG (high dose) treated

group co-administered with vit E this website (high or low dose) and MSG (high dose) followed by administration of Se either (high or low dose) elicited slight decrease in CAT activity as compared with normal control group, but afforded significant increase in CAT activities as compared with MSG-treated groups either in (high, med or low Thymidylate synthase doses) as this effect was much less intense in groups treated with either MSG with vit E or Se. It was obvious from table that treatment of normal rats with MSG in three doses (high, med or low) elicited significant decrease in SOD activity as compared with control group, at the same time, the administration of vit E in either high or low doses afforded non-significant decrease in SOD activity as compared to normal control group. However, Se- treated group at low dose afforded significant decrease in SOD activity as compared to control group. Meanwhile, Se-treated animals at high dose exhibited non-significant decrease in SOD activity when compared with control group. At the meantime, MSG treated groups in (High, med and low doses) afforded significant increase in SOD as compared to normal control group; meanwhile they elicited significant decrease with respect to normal control group. Administration of MSG in three doses (high, med or low doses) induced significant decrease in GPx activity as compared to control group.