They were also more likely to be treated with a selleck kinase inhibitor sedative or hypnotic, but less likely to receive a neuroleptic or a herbal medication. With regard to the type of antidepressant prescribed, modern antidepressants, such as noradrenergic and specific serotonergic antidepressants or selective serotonin reuptake inhibitors (SSRIs), were more likely to be prescribed for patients
diagnosed with depression than tricyclic Inhibitors,research,lifescience,medical antidepressants. These findings were by and large confirmed in a more recent primary care study using the identical design in Scandinavia31 (Munk Jurgensen, personal communication). In accordance with previous research, the Depression 2000 study29 showed that the correct recognition of depression and the likelihood of receiving adequate treatment were associated with a similar set of predictors on the patient’s side: older Inhibitors,research,lifescience,medical age, prior depression or treatment history, depressed
mood as the primary nevertheless reason for consulting the doctor, and suicidal ideation. Current severity also had an effect (odds ratio [OR] 1.2), although not as great as that associated with the other factors. On the doctor’s side, surprisingly few predictors were identified: doctors who had attended a high number of courses on depression in the previous 2 years had a greater probability of correctly recognizing a patient Inhibitors,research,lifescience,medical with depression (OR 2.1); doctors with > 20 years of experience (ie, the older doctors in the sample) Inhibitors,research,lifescience,medical had a considerable lower recognition
rate (OR 0.5). Taking their attitudes toward depression into account and their theoretical background, the authors speculate that older doctors tend to rely heavily on the traditional nosologleal classification systems, Inhibitors,research,lifescience,medical which differentiate between endogenous versus neurotic and reactive depression. This subgroup of older – and seemingly more experienced- doctors were particularly poor at recognizing depression in young people. The study29,30 concluded that, despite numerous attempts to improve doctors’ recognition rates and prescription of appropriate treatment, only modest improvements Cilengitide have been made. Moreover, although GPs manage the typical severe, melancholic patient relatively well, marked deficits were evident for young patients, new cases of incident depression, and cases with comorbidity with other mental disorders. The major barriers for improved recognition and treatment in this study were the time burden of the treating physician and failure to adopt the current descriptive way of diagnosing depression, as opposed to the traditional nosological approach. Anxiety disorders In contrast with the large number of studies in depression, anxiety disorders remain a relatively neglected topic of systematic primary care research.