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to doxorubicin. Mol Cancer 2010, 9:314.CrossRef Competing interests The authors declare that they have no competing interests. Authors’ contributions TY, LFH, ZCN and JYS performed the majority of experiments; see more SSC and TY designed the study and wrote the manuscript; TY and JYS edited the manuscript. All authors read and approved the final manuscript.”
“Background Lung cancer is one of the leading causes of deaths globally. An estimated 222,520 new cases of lung cancer were reported in 2010, which accounted for approximately 15% of cancer diagnoses. This disease accounts for a higher percentage of deaths than any other cancer in both men and women. An estimated 157,300 deaths, which accounted for approximately Verteporfin chemical structure 28% of all cancer deaths, were reported in 2010 .
The high rate of mortality is most likely attributed to early metastasis that causes malignant cells to spread to Anlotinib mw various tissues including bone, brain, and liver tissues. The early detection of cancer leads to a better prognosis for reduced mortality and morbidity. The advent of new and emerging molecular, genetic, and imaging technologies has broadened the possible strategies for early detection and prevention. However, the decrease in mortality should be supported by clinical evidence. Proteomics has recently emerged as a powerful technology to identify differential protein expressions associated with cancer development and progression. New strategies that facilitate proteomic analysis by mass spectrometry (MS) have been introduced for biomarker discovery research.