The Indian Journal of Critical Care Medicine, 2023, presented articles on pages 127 through 131 of volume 27, issue 2.
Saxena AK, Singh A, Salhotra R, Bajaj M, Sharma SK, Singh D, et al. Impact of a hands-on COVID-19 oxygen therapy training program on healthcare workers' ability to retain knowledge and successfully use the skills learned. Volume 27, number 2 of the Indian Journal of Critical Care Medicine, published in 2023, investigates critical care medicine, particularly on pages 127 to 131.
In critically ill patients, delirium is a frequently encountered, often unrecognized, and frequently fatal condition, marked by a sudden disturbance of attention and cognitive function. Outcomes suffer from the fluctuations in global prevalence. Few Indian studies have fully and systematically investigated delirium.
The incidence, forms, predisposing factors, difficulties, and resolution of delirium in Indian intensive care units (ICUs) will be studied in a prospective observational investigation.
Of the 1198 adult patients screened during the study period from December 2019 to September 2021, 936 were ultimately included in the analysis. Utilizing the Richmond Agitation-Sedation Scale (RASS) and the Confusion Assessment Method-Intensive Care Unit (CAM-ICU), a psychiatrist or neurologist further verified the diagnosis of delirium. A comparative analysis of risk factors and associated complications was performed using a control group as a reference.
Delirium presented in a substantial 22.11 percent of critically ill patients. A striking 449 percent of the cases exhibited the hypoactive subtype. Factors associated with higher risk included increasing age, a higher APACHE-II score, hyperuricemia, elevated creatinine, hypoalbuminemia, hyperbilirubinemia, alcohol abuse, and smoking. Significant factors that contributed to the situation included patients on non-cubicle beds, their close positioning to the nursing station, their requirement for ventilation, and the concurrent usage of sedatives, steroids, anticonvulsants, and vasopressors. In patients categorized as delirium, observed complications included the unintentional removal of catheters (357%), aspiration (198%), the necessity for reintubation (106%), decubitus ulcer formation (184%), and a substantial mortality rate (213% compared to 5%).
Indian ICUs frequently experience delirium, a factor that may impact both length of stay and mortality. Establishing the incidence, subtype, and risk factors is the initial approach for preventing this substantial cognitive dysfunction in the intensive care unit.
The listed contributors to the research are A.M. Tiwari, K.G. Zirpe, A.Z. Khan, S.K. Gurav, A.M. Deshmukh, and P.B. Suryawanshi.
An Indian intensive care unit's prospective observational study delved into the incidence, subtypes, risk factors, and outcomes of delirium. Senexin B inhibitor The second issue, 2023, of volume 27 of the Indian Journal of Critical Care Medicine comprises research articles, detailed on pages 111 to 118.
A collaborative research effort involved Tiwari AM, Zirpe KG, Khan AZ, Gurav SK, Deshmukh AM, Suryawanshi PB, and other researchers. Prospective observational study from Indian ICUs, examining the incidence, subtypes, risk factors, and outcomes of delirium. The Indian Journal of Critical Care Medicine, in its 27th volume, issue 2, of 2023, presents findings on pages 111 through 118.
Emergency department patients requiring non-invasive mechanical ventilation (NIV) are screened using the HACOR score. This score factors in modified heart rate, acidosis, consciousness, oxygenation, and respiratory rate, and incorporates pneumonia, cardiogenic pulmonary edema, ARDS, immunosuppression, septic shock, and the SOFA score's influence on NIV efficacy. To replicate a similar distribution of baseline characteristics, propensity score matching could have been a viable strategy. Defining respiratory failure severe enough to necessitate intubation requires objective and specific criteria.
In a study, Pratyusha K. and Jindal A. examine the failure of non-invasive ventilation, concentrating on prevention and prediction methods. Senexin B inhibitor The 2023 second issue of the Indian Journal of Critical Care Medicine, volume 27, presented the content on page 149.
K. Pratyusha and A. Jindal's work, 'Non-invasive Ventilation Failure – Predict and Protect,' presents a comprehensive analysis of the subject. The Indian Journal of Critical Care Medicine, 2023, volume 27, issue 2, presented an article, which is available on page 149.
The existing records concerning acute kidney injury (AKI), including cases of community-acquired (CA-AKI) and hospital-acquired (HA-AKI) AKI amongst non-COVID patients from intensive care units (ICU) throughout the COVID-19 pandemic are insufficient. Our strategy involved a comparative analysis of patient attributes, contrasting them with the pre-pandemic scenario.
This observational prospective study, focused on non-COVID patients, was undertaken in four ICUs of a North Indian government hospital during the COVID-19 pandemic, to evaluate AKI outcomes and mortality predictors in this patient population. Renal and patient survival after ICU transfer and hospital discharge, ICU and hospital stay length, indicators for mortality, and dialysis needs at discharge were scrutinized. Participants exhibiting current or prior COVID-19 infection, a prior history of acute kidney injury (AKI) or chronic kidney disease (CKD), or having donated or received a transplanted organ were excluded from the study.
Of the 200 AKI patients without COVID-19, the most frequent comorbidities, listed in descending order, were diabetes mellitus, primary hypertension, and cardiovascular diseases. Post-surgical patients, alongside systemic infections and severe sepsis, comprised the leading causes of AKI. Dialysis requirements, at the time of ICU admission, during the ICU stay, and beyond 30 days of ICU treatment, were observed in 205, 475, and 65% of patients, respectively. The occurrence of CA-AKI and HA-AKI totaled 1241 cases, while the need for dialysis lasting over 30 days amounted to 851 cases. The mortality rate after 30 days reached the figure of 42%. The hazards associated with hepatic dysfunction (HR 3471), septicemia (HR 3342), age above 60 (HR 4000), and a higher SOFA score (HR 1107) significantly contributed to the overall outcome.
Among the diagnoses, 0001, a medical code, and anemia, a blood condition, were noted.
The laboratory results revealed a deficiency of serum iron, measured at 0003.
These factors emerged as critical indicators for mortality in patients with AKI.
The COVID-19 pandemic, through the restriction of elective surgeries, led to a greater prevalence of CA-AKI relative to HA-AKI compared to the pre-COVID-19 period. Elderly patients with sepsis, exhibiting acute kidney injury affecting multiple organs, hepatic dysfunction, and high SOFA scores, faced heightened risk of adverse renal and patient outcomes.
B. Singh, P.M. Dogra, V. Sood, V. Singh, A. Katyal, and M. Dhawan.
Data from four intensive care units, examining acute kidney injury (AKI) among non-COVID-19 patients during the COVID-19 pandemic, focusing on mortality, outcomes, and the disease spectrum. Articles in the Indian Journal of Critical Care Medicine's 2023 second issue of volume 27, run from page 119 to 126.
Researchers B. Singh, P.M. Dogra, V. Sood, V. Singh, A. Katyal, and M. Dhawan, along with their colleagues, et al. Acute kidney injury outcomes and mortality predictors for non-COVID-19 patients, a study using data collected in four intensive care units during the COVID-19 pandemic, focusing on the spectrum of disease. Senexin B inhibitor Critical care medicine in India, as published in the Indian Journal in 2023 (volume 27, issue 2), detailed research from pages 119-126.
A study explored the feasibility, safety, and practical application of transesophageal echocardiographic screening in patients with COVID-19 ARDS, who were mechanically ventilated and positioned prone.
A prospective observational study took place in an intensive care unit focusing on patients 18 years of age and older with ARDS and undergoing invasive mechanical ventilation during the post-procedure period (PP). Eighty-seven patients were chosen for the study in total.
Regarding ventilator settings, hemodynamic support, and the ultrasonographic probe's insertion, everything ran smoothly and required no change. The average time spent on transesophageal echocardiography (TEE) was 20 minutes. The assessment showed no disruption to the placement of the orotracheal tube, no instances of vomiting, and no gastrointestinal hemorrhage. A frequent complication, nasogastric tube displacement, was observed in 41 (47%) patients. The examination revealed severe right ventricular (RV) impairment in 21 (24%) patients and a diagnosis of acute cor pulmonale in 36 (41%) patients.
Our study underscores the need for continuous RV function assessment during severe respiratory distress and highlights TEE's value for hemodynamic evaluations in post-partum patients (PP).
Including Sosa FA, Wehit J, Merlo P, Matarrese A, Tort B, and Roberti JE, a collective effort.
Prone positioning in COVID-19 patients with severe respiratory distress: A feasibility study utilizing transesophageal echocardiographic assessment. Within the Indian Journal of Critical Care Medicine's 27th volume, second issue of 2023, pages 132-134 held specific content.
Among the researchers, Sosa FA, Wehit J, Merlo P, Matarrese A, Tort B, Roberti JE, et al., contributed their expertise to the project. Feasibility study: transesophageal echocardiographic assessment in prone COVID-19 patients experiencing severe respiratory distress. Within the pages 132 to 134 of the Indian Journal of Critical Care Medicine, 2023, volume 27, issue 2, relevant articles resided.
For critically ill patients requiring endotracheal intubation, videolaryngoscope use has gained prominence, emphasizing the importance of expertise in handling these instruments. Within the intensive care unit (ICU), this study compares the efficacy and outcomes of the King Vision video laryngoscope (KVVL) to those of the Macintosh direct laryngoscope (DL).