We carried out an extensive review of the English-language literature and found that there was little high-level evidence Navitoclax research buy in this field, and no systematically described practical manual for the field. Most importantly, there are no standardized diagnostic criteria and therapeutic management guidelines for ASBO, therefore, we would like to establish standards for these items. The Bologna Guidelines include evidence-based

medicine and reflect the international consensus obtained through earnest discussions among professionals in the field on 1-3 July, 2010, at the Belmeloro Convention Center, Bologna, Italy. Notes on the use of the Guidelines The Guidelines are evidence-based, with the grade of recommendation also based on the evidence. The Guidelines present the diagnostic and therapeutic methods for optimal management and prevention of ASBO. The practice

Guidelines promulgated in this work do not represent a standard of practice. They are suggested plans of care, based on best available evidence and the consensus of experts, but they do not exclude other approaches as being within the standard of practice. For example, they should not be used to compel adherence to a given method of medical management, which method should be finally determined after taking account of the conditions at the relevant medical institution (staff levels, experience, equipment, etc.) Idelalisib order and the characteristics of the individual patient. However, responsibility for the results of treatment rests with those who are directly engaged therein, and not with the consensus group. Methods – Consensus Development In the Consensus Conference on July 2nd 2010, the expert panel had two meetings and a further plenary session. The aim was to focus and clarify the diagnostic and therapeutic issues of the complex management of ASBO, leading to new clinical guidelines, updated and including a wide range of recommendations, for diagnosis, non operative management, timing for surgery, type of surgery and prevention strategies of peritoneal post-operative adhesions causing small bowel obstruction. Based on the review of the current literature, check a panel of worldwide experts were invited to participate

in the development of the new guidelines. All members of the expert panel were asked to define ASBO. For each step of diagnosis, treatment (conservative and surgical) and prevention of ASBO, one expert summarized the current state of the art. From the evidence based presentations and the reported statements as well as from the results of the relevant literature review, a preliminary document with the resume of the Consensus Statements and Recommendations was compiled. For every key statement, the discussion within the expert panel with the involvement of the audience, took place until a 100% consensus within the group and the audience was achieved. Comments from the audience were collected and partly included in the manuscript.