24, 95% CI 0.11-0.38). Children exposed prenatally to short-term

use of paracetamol (1-27 days) also had poorer gross motor outcomes (beta 0.10, 95% CI 0.02-0.19), but the effects were smaller than with long-term use. Ibuprofen exposure was not associated with neurodevelopmental outcomes.

Conclusion Children exposed to long-term use of paracetamol during pregnancy had substantially adverse developmental outcomes at 3 years of age.”
“BACKGROUND: The treatment of familial PF-562271 hyperchylomicronemia presenting in early childhood with episodes of pancreatitis has been ineffective, and affected patients remain at risk for pancreatitis.

OBJECTIVE: To report on the effect of orlistat in siblings with severe inherited hyperchylomicronemia and to assess posttreatment lipoprotein concentrations and composition.

METHODS: Serial observations of plasma lipid levels and hospitalizations after treatment with orlistat and lipoprotein studies on a single fasting posttreatment sample.

RESULTS: The affected siblings inherited a lipoprotein lipase gene mutation from each of their parents: a novel mutation from their father (c.542G > C, p.G181R)

and a known missense mutation from their mother (c.644G > A, p.G215E). When the boy presented to us at age 9 years of age and his sister at age 7 years, we found that addition of orlistat, a pancreatic lipase inhibitor, at a dose of 120 mg given before three low-fat meals a day was effective in reducing episodes of pancreatitis in the boy and in maintaining the triglyceride at lower levels in both children. Cilengitide order During treatment, the children were observed to have elevations in apolipoprotein (apo)B, low-density lipoprotein particle concentration, abnormal apoB-containing subclasses, and deficiencies in apoA-I and apoA-II-containing lipoproteins, changes consistent with continuing increased cardiovascular risk.

CONCLUSION: The data support the need for

more effective long-term treatments that not only prevent pancreatitis but also offset cardiovascular risk. Orlistat can be considered effective in augmenting the effect of a low-fat diet and reducing risk for pancreatitis. (C) 2013 National Lipid Association. All rights reserved.”
“Purpose dbcAMP of review

This study presents the findings from a scoping review of recent, original research investigating changes in brain structure and/or function following pediatric concussion or mild traumatic brain injury (mTBI) using MRI and functional MRI techniques.

Recent findings

Our scoping review identified only five studies, two of which were focused specifically on sports-related concussion. A common finding across studies was that traditional structural methods such as anatomical T1, T2, and even susceptibility-weighted MRI failed to reveal abnormalities in brain structure following pediatric concussion/mTBI.

02). Patients’ preferences were independently associated with AZD1208 their reported involvement

in decision-making about surgery (p=0.01). A fully passive role in decision-making about chemotherapy and AET was more likely to be reported by patients who perceived their involvement in decision-making about surgery as having been fully passive (adjusted odds ratio=4.8, CI95% [2.7-8.7], and adjusted odds ratio=9.8, CI95% [3.3-29.2], respectively). This study shows a significant relationship between the use of antidepressants and involvement in decision-making about surgery, and confirms the relationship between impaired quality of life (in the psychological domain) and a fully passive role in decisions about cancer treatment.

ConclusionsPatients’ involvement in decision-making about chemotherapy and AET was strongly influenced by their experience of decision-making about surgery,

regardless of their tumor stage and history of breast or ovarian cancer. When decisions are being made about surgery, special attention should be paid to facilitating breast cancer patients’ involvement in the decision-making. Copyright (c) 2013 John Wiley & Sons, Ltd.”
“An elegant theory that links hippocampal neurogenesis to mood and anxiety disorders and to the mechanism of action of antidepressant drugs has gained widespread attention. However, depression and anxiety disorders involve multiple areas of the brain, such as the amygdala and prefrontal cortex, where neurogenesis does not FG-4592 research buy appear to occur in the adult mammalian brain. A complementary theory is proposed here in which neurogenesis is seen as an

epiphenomenon of a more widespread alteration in dendritic length and spine number. According to this theory, exposure to chronic stress and stressful life events increases excitotoxic glutamatergic neurotransmission in multiple brain areas. To protect neurons from consequent apoptosis, dendrites retract and spine number decreases, thus limiting the number of exposed glutamate receptors. Drugs that reduce glutamatergic neurotransmission under these circumstances, many of which have already been shown helpful in treating mood and anxiety disorders, may prevent this dendritic retraction find more and thus protect synaptic connections throughout the brain. (The Journal of Neuropsychiatry and Clinical Neurosciences 2010; 22:256-264)”
“Purpose: To determine whether arterial spin-labeling (ASL) magnetic resonance (MR) imaging findings at baseline and early during antiangiogenic therapy can predict later resistance to therapy.

Materials and Methods: Protocol was approved by an institutional animal care and use committee. Caki-1, A498, and 786-0 human renal cell carcinoma (RCC) xenografts were implanted in 39 nude mice. Animals received 80 mg sorafenib per kilogram of body weight once daily once tumors measured 12 mm.

5. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 115:1176-1179, 2010″
“We analyzed the presence or absence of intradural hemorrhage (IDH) and subdural hemorrhage (SDH) and the degree of hypoxic-ischemic

encephalopathy (HIE) in the brain of all nonmacerated fetuses of >24 weeks, neonates, and children up to 3 years of age who died of natural causes over a defined period. We looked into the cause of death and the performance of cardiopulmonary resuscitation in our cohort. The IDH was classified as macroscopic or negative/microscopic only; the HIE was classified as absent, indeterminate, or definite. In fetuses, SDH with IDH was present in 22%; IDH alone MK-2206 concentration was present in 31%, and there was no or minimal hemorrhage in 47% of cases. In infants BAY 80-6946 and children SDH with IDH was present in 19%; IDH alone was present in the 32%, and there was no or minimal hemorrhage in 49% of cases. There was a statistically significant correlation between SDH and HIE, especially in infants and children (P < 0.001). When cases were grouped per age, a significant association between age and hemorrhage (P < 0.0001) was demonstrated, SDH being more common in infants <= 1 month corrected age. Intradural hemorrhage can be the source of thin-film SDH in fetuses, infants, and young children. The presence of SDH is associated

with hypoxia. Intradural and subdural hemorrhages are more common in autopsies of infants under 1 month corrected age. Although more rare, they can also be found in children between 1 month and 3 years of age in the absence of trauma.”
“Psoas

abscess is rarely encountered in obstetric practice. This condition may be primary or secondary resulting EX 527 inhibitor from extension of an infectious process near the psoas muscle. We report a series of three patients with psoas abscess that were encountered in our obstetric practice. Two of these patients had a primary and one a secondary abscess. Two patients underwent laparotomy and drainage of abscess while one received medical treatment. All patients recovered uneventfully.”
“We have theoretically and experimentally investigated the dielectric behavior of NixCo1-xFe2O4 nanoparticles (NPs) (where x=0.0, 0.6, and 1.0), which have been synthesized by microwave induced combustion synthesis using urea as fuel. A variation of complex dielectric permittivity at room temperature with frequency in the range 1 MHz-3 GHz has been studied. The permittivity displays atomic polarization and electronic polarization. Particles showed phase purity and crystallinity in powder x-ray diffraction (XRD) analysis. At the same time, NixCo1-xFe2O4 NPs demonstrated a spinel cubic structure from XRD results.”
“An electrically responsive hydrolyzed polyacrylamide-grafted-sodium alginate (H-PAAm-g-SA)-based membrane-controlled transdermal drug delivery systems were developed and evaluated.

In session 3, all MR images were analyzed together. The diagnostic performance of each MR technique and each reader was evaluated by using receiver operating characteristic (ROC) analysis; differences between postferucarbotran gadobutrol-enhanced,

ferucarbotran-enhanced, and double-contrast MR imaging were assessed at Wilcoxon signed rank testing; and interreader agreement was assessed at Cohen kappa analysis. Histopathologic confirmation or an unchanged clinical course or MR finding was the reference standard.

Results: The four readers’ detection of the benign and malignant lesions was not significantly different (P >= .11) between the three MR techniques. The benign and malignant focal liver lesions were differentiated with significantly higher confidence (P <= .01) on the double-contrast (area under ROC curve [A(z)] = 0.988) and ferucarbotran-enhanced Apoptosis Compound Library (A(z) = 0.985) MR images than on the dynamic gadobutrol-enhanced images (A(z) = 0.963). Accuracy in the diagnosis of hepatocellular carcinoma (HCC) was highest (P = .02) and confidence in the final diagnosis of HCC (P = .001) or metastasis (P = .049) was significantly higher with double-contrast imaging.

Conclusion: In select

cases, double-contrast MR imaging can improve diagnostic accuracy and increase confidence in characterizing focal liver lesions as HCC or metastasis. (C) RSNA, 2009″
“Objective: To investigate the single nucleotide polymorphism 12 (SNP12) in the estrogen receptor a (ESR1) gene in hypospadiac or cryptorchid patients from Northwestern China. Methods: 103 patients and 40 controls were analyzed for SNP12 to verify whether this selleckchem genetic variant was associated with hypospadias or cryptorchidism. Results: The frequencies of the A allele and homozygote individuals for the A allele of SNP12 in the hypospadiac group were higher than in the control group, respectively (p = 0.011, p = 0.005). The frequency of the

A allele of SNP12 in the cryptorchid group was higher than in the control group (p = 0.038). However, no significant difference Selleckchem Pitavastatin was observed between the cryptorchid group and control group of homozygote individuals for the A allele of SNP12 (p = 0.070). Conclusions: Our results suggested that the A allele of SNP12 may increase the risk of hypospadias or cryptorchidism. Copyright (C) 2011 S. Karger AG, Basel”
“This manuscript concerns the application of infrared birefringence imaging (IBI) to quantify macroscopic and microscopic internal stresses in multicrystalline silicon (mc-Si) solar cell materials. We review progress to date, and advance four closely related topics. (1) We present a method to decouple macroscopic thermally-induced residual stresses and microscopic bulk defect related stresses. In contrast to previous reports, thermally-induced residual stresses in wafer-sized samples are generally found to be less than 5 MPa, while defect-related stresses can be several times larger.

Amphotericin B has limited activity against Aspergillus terreus and Aspergillus nidulans. Not surprisingly, continued use of azole-based drugs has the undesirable consequence SB202190 of elevating the resistance of subsequent isolates from these patients. Several species in the Aspergillus fumigatus

complex appear to be resistant to azoles; there is evidence of in vitro and in vivo correlation. Each in vitro susceptibility testing method has its own advantages and disadvantages. Etest is easy to perform and use on a daily basis, yet it is expensive. Disk diffusion is the most attractive alternative method to date, yet we lack sufficient data for aspergilli. The European Committee on Antimicrobial Susceptibility Testing (EUCAST) and the Clinical Laboratory Standard Institute (CLSI) have produced reproducible reference testing methods. This article reviews the available methods for antifungal susceptibility see more testing in Aspergillus spp. as well as the scant data regarding the clinical implications of in vitro testing.”
“We present a model to calculate the gain recovery of quantum cascade lasers (QCLs). We implement the model for two QCLs with different material systems and quantum mechanical designs. It is found that both incoherent scattering and coherent tunneling are important for gain recovery, however, their relative importance depends on the material systems, quantum

mechanical designs, and operating conditions. Though details of the gain recovery vary for the two QCLs, a complete gain recovery takes similar to 2 ps in both cases. The results are consistent with the results found in pump-probe experiments. (C) 2011 American Institute of Physics. [doi:10.1063/1.3544201]“
“Four novel highly soluble p-/n-poly[(2,5-divinyl-3,4-dialkylthiophene)-alt-2,6-pyridine] (PA(2)TV-Py) and poly[(2,5-divinyl-3,4-dialkylthiophene)-alt-(2,5-diphenyl-1,3,4-oxadiazole)] (PA(2)TV-OXD) are prepared by Heck coupling approach to compare their photoelectric properties. Characterizations of the copolymers include FT-IR, (1)H-NMR, gel permeation chromatography (GPC), thermogravimetric analysis (TGA), UV-vis spectroscopy,

photoluminescence (PL), and electroluminescence (EL). Four alt-copolymers exhibit excellent solubility in common organic solvents (e. g., CHCl(3), THF) and good thermal stabilities, losing AZD7762 order less than 5% on heating to similar to 250 degrees C. The optical properties depict that the band-gap energy of PA(2)TV-Py and PA(2)TV-OXD is similarly, ranging from 2.68 to 2.80 eV in solid film and 2.90-2.97 eV in CHCl(3) solution. PA(2)TV-Pys can emit bright turquoise light with quantum efficiencies (QE) of 30.6 and 53.9%, which about 10-18 times higher than that of homopolymer in CHCl(3) solution. Furthermore, the QE of two PA(2)TV-OXDs (purple fluorescence) are increased to 43.6 and 68.5%, respectively, about 1.3-1.4 times higher than that of PA(2)TV-Pys.

The role of the PFC becomes predominant when time intervals have to be kept in memory, especially for longer supra-second time intervals, or when the task requires a high cognitive level. We conclude that the contribution of these strongly interconnected anatomical structures in time processing is not fixed, depending not only on the duration of the time interval to be assessed by the brain, but also on the cognitive set, the chosen task and the stimulus modality.”
“RN Channick. selleck screening library Pulmonary hypertension: Classification and treatment. Can J Cardiol 2010;26(Suppl

B):5B-11B.

Pulmonary hypertension (PH) comprises a variety of conditions that lead to elevated pulmonary arterial pressure. Because the treatment for PH depends on the cause, it is critical to accurately

classify the cause of the problem. A useful classification system, developed and refined at the World Conference on Pulmonary Hypertension, held every five years, has been developed. In this system, patients can be classified as having PH due to the following: pulmonary arterial hypertension (PAH); left-sided heart disease; lung or respiratory disease; chronic thromboembolic disease; or multi factorial selleck chemical or unclear mechanisms. Although challenges in classifying patients remain, such as the patient with some left-sided heart disease but ‘out of proportion’ PH, this system has been critical in helping guide therapy. For patients who are deemed to be in group 1 (PAH) several approved therapies are available, including prostanoids (available in intravenous, subcutaneous and inhaled forms), endothelin receptor antagonists and phosphodiesterase type 5 inhibitors. Each of these agents has been approved based on improvement in exercise capacity demonstrated in randomized controlled trials. A treatment algorithm that provides guidance for choosing the appropriate treatment for PAH patients has been published. Patients who are considered to be ‘high risk’, such is those with overt right heart

failure, are generally appropriate for parenteral therapy, whereas those who are only moderate or low risk ire usually candidates for initial oral therapy. selleckchem In addition, close follow-up allows for the consideration of additional therapies. Many current trials, in fact, are studying this ‘goal-directed’ approach to the treatment of PAH.”
“A systematic review was carried out to study the hypothesis that bladder wall thickness (BWT) on ultrasound is accurate in diagnosing detrusor overactivity (DO).

Databases were searched from database inception to January 2009. Two reviewers independently selected articles and extracted data on study characteristics, quality and results.

Five out of 190 screened studies were included. There were variations in the quality, methods of performing the ultrasound and urodynamics studies, and the format of reporting findings.

In vitro release studies in phosphate buffer saline (pH 7.4) evidenced a burst release in the first 1 h, followed by a sustained release in the residual time. The release amount of SA and GM were approximately equal in 24 h, which indicated that the SA- and GM-loaded O-CMC nanoparticles are a promising carrier system for inhibiting

the ototoxicity of GM. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 123: 1684-1689, 2012″
“The LATERAL ORGAN BOUNDARIES DOMAIN (LBD) gene family encodes plant-specific transcription factors. In this report, the LBD gene DOWN IN DARK AND AUXIN1 (DDA1), which is closely related to LATERAL ORGAN BOUNDARIES (LOB) and ASYMMETRIC LEAVES2 (AS2), was characterized. DDA1 is expressed primarily in vascular tissues and its transcript levels were reduced by exposure to exogenous indole-3-acetic acid (IAA or auxin) and in response see more to dark exposure. Analysis of a T-DNA insertion line, dda1-1, in which the insertion resulted in misregulation of DDA1 transcripts in the presence of IAA and in

the dark revealed possible functions in auxin response and photomorphogenesis. dda1-1 plants exhibited reduced sensitivity to auxin, produced fewer lateral roots, and displayed aberrant hypocotyl elongation in the dark. Phenotypes resulting from fusion of a transcriptional Pexidartinib cell line repression domain to DDA1 suggest that DDA1 may act as both a transcriptional activator and a transcriptional repressor depending on the context. These results

check details indicate that DDA1 may function in both the auxin signalling and photomorphogenesis pathways.”
“Insecticide-treated nets (ITNs) and indoor residual spraying (IRS) are currently the preferred methods of malaria vector control. In many cases, these methods are used together in the same households, especially to suppress transmission in holoendemic and hyperendemic scenarios. Though widespread, there has been limited evidence suggesting that such co-application confers greater protective benefits than either ITNs or IRS when used alone. Since both methods are insecticide-based and intradomicilliary, this article hypothesises that outcomes of their combination would depend on effects of the candidate active ingredients on mosquitoes that enter or those that attempt to enter houses. It is suggested here that enhanced household level protection can be achieved if the ITNs and IRS have divergent yet complementary properties, e. g. highly deterrent IRS compounds coupled with highly toxic ITNs. To ensure that the problem of insecticide resistance is avoided, the ITNs and IRS products should preferably be of different insecticide classes, e. g. pyrethroid-based nets combined with organophosphate or carbamate based IRS. The overall community benefits would however depend also on other factors such as proportion of people covered by the interventions and the behaviour of vector species.

Materials and Methods: Between March and June 2009, an internet-based

survey was performed among board-certified urologists of the EAU who treated >= 10 patients with metastatic PCa annually. Results: Questionnaires completed by 200 LDC000067 solubility dmso urologists from 12 European countries including 27,442 PCa patients were used for analyses. On average, 22% of the patients presented in stage IV, 15% had bone metastases and 10% received BPs. In most countries, BPs were used to the same extent in hormone-naive and castration-resistant PCa (CRPC). A total of 23% of urologists prescribed chemotherapy in patients with hormone-sensitive PCa, and 55% of the urologists did not administer androgen deprivation NCT-501 purchase maintenance therapy in patients with CRPC. Conclusions: BPs were frequently used in PCa with bone metastases, although current guidelines recommend their use only in CRPC. Standardized multidisciplinary

educational programs should be developed in order to prevent non-indicated early chemotherapy in hormone-sensitive patients and to stimulate maintenance of androgen deprivation therapy in CRPC patients. Also, programs facilitating home infusions for patients who need intravenous BPs are needed in specific countries to optimize treatment of CRPC. Copyright (C) 2012 S. Karger AG, Basel”
“Pregnancy associated with ovarian tumors was reviewed over a 20-year period to determine the maternal and fetal outcome in patients undergoing surgery during pregnancy.

A retrospective study of 94 cases of ovarian tumors treated surgically during pregnancy was investigated for incidence, clinico-pathological FaraA features and outcome in a teaching hospital between June 1987 and May 2007.

The overall incidence of ovarian tumor in pregnant women

was 1 in 505 (0.2%) deliveries. Diagnosis of 69.2% tumors resulted in the first and second trimesters of pregnancy. Twenty-two (23.4%) patients presented as an emergency at different periods of gestation and 16 (17.1%) tumors were incidentally discovered at cesarean section which underlines the significance of examining the ovaries routinely at cesarean section. Benign teratoma (39.4%) and serous cystadenoma (24.5%) were the most common types of ovarian tumors found in the study. The incidence of malignant tumors was 5.3%. Tumors with low malignant potential comprised 40% of malignancy. The miscarriage rate after surgery was 44.4% in the first trimester compared with 16.6% in the second trimester. The preterm birth rate was 4.3% in the series.

The value of clinical and ultrasound examinations in early pregnancy as a diagnostic aid is highlighted. Whenever an ovarian tumor is detected in pregnancy, malignancy should always be suspected. Treatment of an ovarian tumor in pregnancy should be tailored according to the age, parity, clinical presentation, gestational age and histopathology of the tumor.

67

or 2 mm thick) that were interpreted by interactively adjusting the viewing thickness and viewing plane. The CT readings were retrospectively compared with surgical and pathologic findings. LY333531 manufacturer In patients in whom the presence of PM was rated as grade 1 or less, factors predictive of PM were identified by testing variables, including patient and tumor characteristics, with univariate tests and multivariate logistic regression analysis.

Results: Fifty-three patients (10.6%) had confirmed PM. When only grade 2 was considered to indicate a positive CT reading, sensitivity and specificity were 28.3% (15 of 53) and 98.9% (440 of 445), respectively. With the threshold of grade 1 or greater GSK1838705A datasheet indicating a positive reading, sensitivity and specificity were 50.9% (27 of 53) and 96.2% (428 of 445), respectively. In the patients with grades of 1 or less, the significant factors predictive of

PM were greater tumor size and T stage.

Conclusion: The sensitivity of PM detection is limited, even with modern CT techniques. In patients whose CT results are not definitely positive for PM, staging laparoscopy is still recommended if the aforementioned two predictive factors (greater tumor size and T stage) are suspected. (C) RSNA, 2009″
“Coinfection with hepatitis B virus (HBV) is an important and preventable cause of chronic liver disease among HIV-infected patients. We calculated ATM Kinase Inhibitor clinical trial the prevalence of chronic HBV infection annually from 1996 to 2007 by age, gender, race/ethnicity, and HIV transmission risk in a multisite

observational cohort study of HIV-infected patients. Prevalence of chronic HBV infection was calculated as the number of patients with a positive HBsAg or detectable HBV DNA divided by the number of patients tested using either one of these assays. Among 4467 (59%) patients tested for chronic HBV infection from a total of 7618 patients active during 1996-2007, median age was 38.5 years, 77% were men, 49% were white, 35% were black, 13% were Hispanic, and 53% were men who had sex with men (MSM). Overall, 8.4% tested positive for HBsAg or detectable HBV DNA. Annual chronic HBV prevalence during 1996-2007 ranged from 7.8% to 8.6% without a statistically significant trend. Overall, prevalence was greater among men compared with women; among whites, blacks, and persons of other race compared with Hispanics; among MSM compared with injection drug users and high-risk heterosexuals; and among patients aged 35-44 years compared with younger or older patients. MSM constituted the greatest fraction (63-72%) of all HBV-infected patients in the HIV Outpatient Study (HOPS) over the period. Of eligible patients, 5.8%, 23.4%, and 31.6% had received at least one dose of HBV vaccine by years 1996, 2002, and 2007, respectively.

70) and 0 and 12 months (0.70). Good agreement of quadrant signal after USPIO infusion was shown between 0 and 6 months (0.68) and moderate agreement was shown between 0 and 12 months (0.33). Conclusions: USPIO-enhanced sequential MRI of atheromatous carotid plaques is clinically feasible. This may have important implications for future longitudinal studies involving pharmacologic intervention in large patient cohorts.”
“Stereostructures

Autophagy inhibitor of dentatins A, B and C have been revised to 8-epiisolippidiol-3-O-beta-glucopyranoside, 11 beta,13-dihydro-8-epideacylcynaropicrin-3-O-beta-glucopyranoside and ixerin F, respectively, based on comparative NMR studies of isomeric dehydrocostuslactone derivatives isolated from Crepis species. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.”
“OBJECTIVES: This pilot study was designed to utilize stroke volume variation and cardiac index to ensure fluid optimization during one-lung ventilation in patients undergoing thoracoscopic lobectomies.

METHODS: Eighty patients undergoing thoracoscopic lobectomy were randomized

into either a goal-directed therapy group or a control group. In the goal-directed therapy group, the stroke volume variation was controlled at 10%+/- 1%, and the cardiac index was controlled at a minimum of 2.5 L. min(-1). m(-2). In the control group, the MAP was maintained at between 65 mm Hg and 90 mm Hg, heart rate was maintained at between 60 BPM and 100 BPM, and urinary output was greater than 0.5 mL/kg(-1)/h(-1). The hemodynamic variables, arterial blood gas analyses, total administered selleck products fluid volume and side effects were recorded.

RESULTS: The PaO2/FiO(2)-ratio before the end of one-lung ventilation in the goal-directed therapy group was significantly higher than that of the control group, but there were no differences between the goal-directed

therapy group and the control group for the PaO2/FiO(2)-ratio or other arterial blood gas analysis indices prior to anesthesia. The extubation time was significantly earlier in the goal-directed therapy group, but there was no difference in the length of hospital stay. Patients in the control group had greater urine volumes, and they were given greater colloid and overall fluid volumes. Nausea and vomiting were significantly reduced in this website the goal-directed therapy group.

CONCLUSION: The results of this study demonstrated that an optimization protocol, based on stroke volume variation and cardiac index obtained with a FloTrac/Vigileo device, increased the PaO2/FiO(2)-ratio and reduced the overall fluid volume, intubation time and postoperative complications (nausea and vomiting) in thoracic surgery patients requiring one-lung ventilation.”
“Cerebellar long-term depression (LTD) is a form of long-term synaptic plasticity that is triggered by calcium (Ca2+) signals in the postsynaptic Purkinje cell.